Document Detail


Blood pressure response to potassium supplementation in normotensive adults and children.
MedLine Citation:
PMID:  3653972     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To investigate the effect on blood pressure of a modest increase in dietary potassium intake, 38 healthy, free-living families were enrolled in a study involving 4 weeks of potassium supplementation. This was preceded by collection of five baseline measurements of blood pressure and urinary electrolyte excretion and followed by a 4-week recovery period. Although there was a significant increase in urinary potassium excretion during supplementation in both adults and children (p less than 0.001), there were no significant changes in systolic, diastolic, or mean arterial blood pressure. Height and weight increased significantly in children (p less than 0.001), and weight increased in adults (p less than 0.01) over the course of the study. Multivariate analysis of variance of blood pressure controlling for these confounding variables failed to reveal any effect of the potassium supplementation on blood pressure. These results suggest that increasing intake of dietary potassium alone in a healthy, free-living normotensive population is unlikely to have a discernible effect on blood pressure.
Authors:
J Z Miller; M H Weinberger; J C Christian
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Hypertension     Volume:  10     ISSN:  0194-911X     ISO Abbreviation:  Hypertension     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-11-16     Completed Date:  1987-11-16     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  437-42     Citation Subset:  IM    
Affiliation:
Hypertension Research Center, Indiana University School of Medicine, Indianapolis 46223.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Pressure / drug effects*
Body Height / drug effects
Body Weight / drug effects
Child
Diet*
Family
Female
Humans
Male
Middle Aged
Potassium / administration & dosage*,  urine
Sodium / urine
Grant Support
ID/Acronym/Agency:
HL-27398/HL/NHLBI NIH HHS; RR00750/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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