Document Detail

Blood pressure response to exercise test and serum lipids in normotensive men with positive family history of hypertension.
MedLine Citation:
PMID:  17243498     Owner:  NLM     Status:  MEDLINE    
The aim of the study was to follow the arterial blood pressure response to exercise test and serum lipids in middle-aged normotensive men with family history (FH) of arterial hypertension. 152 normotensive men, divided into two groups: I group--92 men without FH for arterial hypertension and II group--60 men with family history for arterial hypertension were investigated. The response of blood pressure to exercise test on bicycle ergometer with progressively increasing workload up to 100 W was followed up. Five minute recovery period was followed, too. The total cholesterol (TC), high-density and low-density lipoprotein cholesterol (HDL-C and LDL-C) and triglycerides were assessed and TC/HDL-C ratio was calculated. Significant difference in the arterial blood pressure at a level of 100 W between the Ist and IInd group was found: 177 +/- 19.0/ 89 +/- 12.0 mmHg versus 189 +/- 17**/ 96 +/- 11* mmHg (* p < 0.01, ** p < 0.001). Subjects with positive FH for arterial hypertension showed higher elevation of arterial blood pressure during and after exercise: OR = 2.3 (95% CI 1.1 -4.8). The systolic blood pressure during the recovery period and TC/HDL-C ratio were significantly higher with the Ilnd group. In conclusion, our data show significantly higher reaction of blood pressure to exercise, retarded recovery of blood pressure and significantly higher TC/HDL-C ratio with the individuals with positive FH for arterial hypertension.
Christo Deyanov; Katia Vangelova
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Central European journal of public health     Volume:  14     ISSN:  1210-7778     ISO Abbreviation:  Cent. Eur. J. Public Health     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-01-24     Completed Date:  2007-03-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9417324     Medline TA:  Cent Eur J Public Health     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  186-8     Citation Subset:  IM    
National Center of Public Health Protection, Sofia, Bulgaria.
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MeSH Terms
Blood Pressure / physiology*
Exercise Test*
Genetic Diseases, Inborn*
Hypertension / genetics*
Lipids / blood*
Middle Aged
Prospective Studies
Risk Assessment
Risk Factors
Reg. No./Substance:

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