| Blood pressure and pulse response to insulin-induced hypoglycemia during non-selective and selective beta-blockade. | |
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MedLine Citation:
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PMID: 6112844 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypoglycemia was induced in ten healthy male volunteers during medication with atenolol, metoprolol and propranolol. The beta-blockers abolished the tachycardia during hypoglycemia. In some subjects bradycardia, and in two nodal bradycardia was observed on propranol. The physiologic blood pressure responses were dampend during the beta1-selective blockade. With propranolol a rise in blood pressure was recorded, in two subjects up to 160/105. The blockers had no effect on degree of hypoglycemia or glucose recovery. |
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Authors:
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J Pape; J Jervell; E Anker; H Bergrem; K Dahle; T Leivestad; A vd Lippe; L Myrseth; E Thaulow; H Urving |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Acta medica Scandinavica. Supplementum Volume: 645 ISSN: 0365-463X ISO Abbreviation: Acta Med. Scand. Suppl. Publication Date: 1981 |
Date Detail:
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Created Date: 1981-07-23 Completed Date: 1981-07-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370331 Medline TA: Acta Med Scand Suppl Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 105-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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pharmacology* Adult Atenolol / pharmacology Blood Pressure / drug effects* Heart Rate / drug effects Humans Hypoglycemia / physiopathology* Insulin / pharmacology* Male Metoprolol / pharmacology Propranolol / pharmacology Pulse / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 11061-68-0/Insulin; 29122-68-7/Atenolol; 37350-58-6/Metoprolol; 525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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