| Blood pressure and pressor response to angiotensin II during pregnancy and nursing in the rabbit. | |
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MedLine Citation:
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PMID: 7195865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A continuous study to determine blood pressure and pressor response to angiotensin II (A-2) during pregnancy and postpartum was performed in a chronic rabbit preparation. The resting blood pressure during pregnancy was found to be lower than that in the postpartum period. Pressor response to A-2 was diminished during pregnancy and during nursing, but in the absence of nursing, this response returned to normal values by 1 week postpartum. Inhibition of prostaglandin synthetase caused a significant increase in the pressor response to A-2 during gestation, but did not change the resting blood pressure either before or after delivery. The results are discussed in light of previous animal and human studies, and factors which could affect vascular reactivity during gestation and nursing are analyzed. |
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Authors:
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M Katz; R K Creasy |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 12 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 1981 |
Date Detail:
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Created Date: 1981-09-15 Completed Date: 1981-09-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 211-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiotensin II
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pharmacology* Animals Blood Pressure / drug effects* Female Lactation / drug effects* Pregnancy Pregnancy, Animal / drug effects* Pressoreceptors / drug effects* Rabbits |
| Grant Support | |
ID/Acronym/Agency:
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HD 07162/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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11128-99-7/Angiotensin II |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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