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Blood pressure pattern and heart rate variability in normotensive patients with type 2 diabetes mellitus.
MedLine Citation:
PMID:  21528760     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
MATERIAL AND METHODS: Fifty-two subjects with type 2 diabetes, aged 59 (+/- 6), were consecutively recruited at the Internal Medicine Department of the County Hospital in Cluj. Informed consent was obtained from all participants. A control group of 47 subjects, age and sex matched, was also analyzed.
RESULTS: More than half of the patients had a non-dipping pattern, despite the fact that they are considered normotensive patients. Heart rate variability parameters are lower in the non-dipping group, but the difference is significant only for vagal activity. Left ventricle is thicker in non-dipping group. The mean age of the non-dipping group (61.23 +/- 2.02 years) was significantly higher than the age of the dipping group (55.11 +/- 3.88 years) (p < 0.01).
DISCUSSIONS AND CONCLUSION: We found a great number of patients with diabetes mellitus and with altered patterns of blood pressure, even if they were previously considered as normotensive. The non-dipping pattern is associated with abnormal values of heart rate variability parameters and with thicker left ventricle walls, but the differences are not always statistically significant. It is important to closely monitorize the patients with diabetes mellitus even if they have normal office blood pressure determinations, mainly those with a history of more than 5 years of the disease.
Authors:
Laura Poantă; Anca Cerghizan; Dana Pop
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Romanian journal of internal medicine = Revue roumaine de médecine interne     Volume:  48     ISSN:  1220-4749     ISO Abbreviation:  Rom J Intern Med     Publication Date:  2010  
Date Detail:
Created Date:  2011-05-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304507     Medline TA:  Rom J Intern Med     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  321-7     Citation Subset:  IM    
Affiliation:
"Iuliu Haţieganu" University of Medicine and Pharmacy, Second Department of Internal Medicine, Cluj-Napoca, Romania. laurapoanta@yahoo.com
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