| Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum). | |
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MedLine Citation:
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PMID: 20361714 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Elettaria cardamomum (L.) Maton. (Small cardamom) fruit powder was evaluated for its antihypertensive potential and its effect on some of the cardiovascular risk factors in individuals with stage 1 hypertension. Twenty, newly diagnosed individuals with primary hypertension of stage 1 were administered 3 g of cardamom powder in two divided doses for 12 weeks. Blood pressure was recorded initially and at 4 weeks interval for 3 months. Blood samples were also collected initially and at 4 weeks interval for estimation of lipid profile, fibrinogen and fibrinolysis. Total antioxidant status, however, was assessed initially and at the end of the study. Administration of 3 g cardamom powder significantly (p<0.001) decreased systolic, diastolic and mean blood pressure and significantly (p<0.05) increased fibrinolytic activity at the end of 12th week. Total antioxidant status was also significantly (p<0.05) increased by 90% at the end of 3 months. However, fibrinogen and lipid levels were not significantly altered. All study subjects experienced a feeling of well being without any side-effects. Thus, the present study demonstrates that small cardamom effectively reduces blood pressure, enhances fibrinolysis and improves antioxidant status, without significantly altering blood lipids and fibrinogen levels in stage 1 hypertensive individuals. |
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Authors:
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S K Verma; Vartika Jain; S S Katewa |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Indian journal of biochemistry & biophysics Volume: 46 ISSN: 0301-1208 ISO Abbreviation: Indian J. Biochem. Biophys. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-04-05 Completed Date: 2010-10-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0310774 Medline TA: Indian J Biochem Biophys Country: India |
Other Details:
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Languages: eng Pagination: 503-6 Citation Subset: IM |
Affiliation:
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Indigenous Drug Research Center, Department of Medicine, RNT Medical College, Udaipur 313 001, Rajasthan, India. skvermaster@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antioxidants / pharmacology* Blood Pressure / drug effects* Elettaria* Fibrinolysis / drug effects* Humans Hypertension / metabolism, physiopathology Lipid Metabolism / drug effects Middle Aged Single-Blind Method Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants |
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