Document Detail

Blood pressure, intraocular pressure, and retinal vessels after high altitude mountain exposure.
MedLine Citation:
PMID:  2803164     Owner:  NLM     Status:  MEDLINE    
Identical test protocols were used before and after 2 to 7 weeks of high altitude exposure in 23 climbers participating in 3 separate mountain expeditions in the Himalayas. The three groups reached altitudes of 4,000 m, 5,200, and 5,850 m, respectively. High altitude retinal hemorrhages (HARH) were found in three subjects (13%). Two weeks after the mountain exposure, reduced mean values of systolic (p less than 0.005) and diastolic (p less than 0.05) blood pressure and intraocular pressure (p less than 0.005) were found. Retinal veins were dilated 2.6% (p less than 0.001), and in both arteries (p less than 0.001) and veins (p less than 0.005) we observed a tendency for small vessels to dilate and large vessels to constrict. The intensity of reflection of light ("the central light reflex") from arteries was reduced (p = 0.003), indicating hemorrheology changes in the vessels. This study shows that significant changes in blood pressure, intraocular pressure and retinal vascularity follow hypoxic and physical strain of high altitude. The vascular conditioning of altitude acclimatization can be demonstrated in the retinal circulation 2 weeks after the exposure.
O Brinchmann-Hansen; K Myhre
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aviation, space, and environmental medicine     Volume:  60     ISSN:  0095-6562     ISO Abbreviation:  Aviat Space Environ Med     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-07     Completed Date:  1989-11-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7501714     Medline TA:  Aviat Space Environ Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  970-6     Citation Subset:  IM; S    
Eye Department, Ullevål University Hospital, Oslo, Norway.
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MeSH Terms
Altitude Sickness / epidemiology
Hypotension / epidemiology*
Intraocular Pressure*
Middle Aged
Physical Exertion
Physical Fitness
Retinal Hemorrhage / epidemiology
Retinal Vessels / physiology*

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