Document Detail


Blood pressure and insulin in Ethiopian immigrants: longitudinal study.
MedLine Citation:
PMID:  7595906     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immigration from Ethiopia to Israel exposed subjects from an underdeveloped environment to that of a westernised, developed country. In previous cross-sectional analyses we found that residence in Israel for more than 2 years was associated with a rise in blood pressure which, in turn, was associated with a rise in lipids and insulin levels. Herein we report longitudinal follow-up and baseline examination of 53 young male Ethiopians who resided in a relatively controlled environment (agricultural boarding schools) for 2 years after immigration. Their mean age, when re-examined, was 23 +/- 3 years. Body mass index (20 +/- 2 kg/m2) and triceps' skinfold (71 +/- 32 mm) were not different from baseline values. However, over the 2 years blood pressure rose from 118 +/- 9/62 +/- 11 to 129 +/- 13/71 +/- 10 mmHg, P < 0.0001 for both systolic and diastolic pressures. At 2 years 11 of 53 subjects (20.7%) had hypertension. Total high-density lipoprotein cholesterol and triglyceride levels increased from 131 +/- 27, 36 +/- 8 and 65 +/- 22 mg/dl to 146 +/- 29, 43 +/- 10 and 98 +/- 42 mg/dl, respectively; P < 0.00001 for all. Surprisingly, glucose tolerance (to oral 75 g load) improved and the sum of insulin (first and second hour post-load) decreased significantly and was not correlated with blood pressure changes. Only systolic blood pressure was an independent predictor of incident hypertension (r2 = 0.33, P < 0.0001) in multiple regression analysis.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
M Bursztyn; I Raz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of human hypertension     Volume:  9     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-07-28     Completed Date:  1995-07-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  245-8     Citation Subset:  IM    
Affiliation:
Department of Medicine, Hadassah University Hospitals, Jerusalem, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Pressure*
Body Mass Index
Emigration and Immigration
Ethiopia / ethnology
Glucose Intolerance
Humans
Hypertension / epidemiology
Insulin / blood*
Israel / epidemiology
Longitudinal Studies
Male
Prevalence
Chemical
Reg. No./Substance:
11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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