| Blood pressure in obese adolescents: effect of weight loss. | |
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MedLine Citation:
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PMID: 3288957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The BP distribution of a group of 72 obese adolescents was determined both before and after weight loss. Weight loss was produced by a program of caloric restriction and behavior change alone (n = 26) or with a combination of caloric restriction, behavior change, and exercise (n = 25). It was demonstrated that obese adolescents have a BP distribution that is skewed 1 SD to the right of normal (P less than .01), and that with weight loss this distribution was no longer different from that of the general population. It was also shown that a weight loss program that incorporates exercise and caloric restriction produces the most desirable effect on BP reduction (ie, greatest decrease in resting systolic BP and greatest decrease in exercise diastolic and mean BP). Finally, it was demonstrated that obese adolescents have structural changes present in the forearm resistance vessels and that these structural changes are reversed to the greatest extent in the weight loss program that includes exercise. |
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Authors:
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A P Rocchini; V Katch; J Anderson; J Hinderliter; D Becque; M Martin; C Marks |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pediatrics Volume: 82 ISSN: 0031-4005 ISO Abbreviation: Pediatrics Publication Date: 1988 Jul |
Date Detail:
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Created Date: 1988-07-18 Completed Date: 1988-07-18 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 16-23 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, University of Michigan, Ann Arbor. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adolescent Behavior Analysis of Variance Blood Pressure* Body Composition Body Weight* Child Clinical Trials as Topic Diet, Reducing Energy Intake Female Forearm / blood supply Heart Rate* Humans Male Obesity / diet therapy, physiopathology*, therapy Oxygen Consumption Physical Exertion Random Allocation Regression Analysis Vascular Resistance |
| Grant Support | |
ID/Acronym/Agency:
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2R01-HL-35743/HL/NHLBI NIH HHS; M01-RP00042-21//PHS HHS; R01-AM309-89/AM/NIADDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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