Document Detail

Blood pressure and functional aspects of the aging brain.
MedLine Citation:
PMID:  2589916     Owner:  NLM     Status:  MEDLINE    
This study was carried out to define the effects of both long-term hypertension and hypotension on the cerebral functioning of the elderly, comparing them to the effects of normotension. Ninety-eight subjects of both sexes, between 70 and 82 years of age, were divided into three groups on the basis of their mean blood pressure: 33 normotensives, 36 hypotensives and 29 hypertensives. They underwent a neuropsychological assessment, a haemorrheological evaluation and an EEG monitoring while awake. The results show that the three parameters were almost always within normal limits in the normotensives, while EEG alterations, lower neurophysiological scores and blood hyperviscosity were noted in both the hypertensives and hypotensives. Our results would seem to confirm that long-term hypertension may induce alterations in the cerebral electrogenesis and intellectual functions of the elderly and that also long-term hypotension might negatively interfere with some functional aspects of the aging brain.
L Parnetti; P Mecocci; G Ciuffetti; G Bellomo; U Senin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of gerontology and geriatrics     Volume:  9     ISSN:  0167-4943     ISO Abbreviation:  Arch Gerontol Geriatr     Publication Date:    1989 Sep-Oct
Date Detail:
Created Date:  1990-01-03     Completed Date:  1990-01-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8214379     Medline TA:  Arch Gerontol Geriatr     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  155-61     Citation Subset:  IM    
Aging Brain Research Centre, Chair of Gerontology and Geriatrics, Perugia University, Italy.
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MeSH Terms
Aged, 80 and over
Aging / physiology*
Blood Pressure*
Brain / physiopathology*
Neuropsychological Tests

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