Document Detail

Blood pressure categories and cardiovascular risk factors in Japan: the Jichi Medical School (JMS) Cohort Study.
MedLine Citation:
PMID:  17785933     Owner:  NLM     Status:  MEDLINE    
Few studies have reported on risk factors by blood pressure categories based on antihypertensive treatment in the general population. We examined the associations between blood pressure categories and other risk factors in Japan. Cross-sectional study, multicenter population-based study was designed. A total of 11,302 men and women were eligible. Data were obtained from April 1992 to July 1995 in 12 rural districts in Japan. Subjects were divided into three categories: normotensives (with blood pressure <140/90 mmHg), treated hypertensives (antihypertensive treatment regardless of current blood pressure), and nontreated hypertensives (blood pressure >or=140/90 mmHg without hypertensive treatment). The proportions of normotensives, treated hypertensives, and nontreated hypertensives were 63%, 10%, and 27% among men, and 67%, 13%, and 20% among women, respectively. Total cholesterol, triglyceride, blood glucose, and body mass index were higher in treated or nontreated hypertensives than in normotensives. Fibrinogen, factor VIIc, and physical activity index were higher in treated hypertensives than in normotensives. High-density lipoprotein (HDL) cholesterol was higher in normotensives than in treated or nontreated hypertensives in women; but no tendency was shown in men. The proportions of dyslipidemia, impaired glucose tolerance, and metabolic syndrome were significantly higher in treated and nontreated hypertensives than in normotensive men and women. In conclusion, cardiovascular risk factors were higher in hypertensives with or without treatment than in normotensives in a general population in Japan.
Shizukiyo Ishikawa; Yoshihiro Shibano; Yasuhiro Asai; Kazuomi Kario; Kazunori Kayaba; Eiji Kajii
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hypertension research : official journal of the Japanese Society of Hypertension     Volume:  30     ISSN:  0916-9636     ISO Abbreviation:  Hypertens. Res.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-09-05     Completed Date:  2007-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9307690     Medline TA:  Hypertens Res     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  643-9     Citation Subset:  IM    
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan.
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MeSH Terms
Antihypertensive Agents / pharmacology,  therapeutic use*
Blood Pressure / drug effects,  physiology
Cardiovascular Diseases / epidemiology*,  ethnology
Cohort Studies
Cross-Sectional Studies
Hypertension / drug therapy*,  epidemiology*,  ethnology
Middle Aged
Prospective Studies
Risk Factors
Reg. No./Substance:
0/Antihypertensive Agents

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