Document Detail

Blood pressure and both venous and urinary catecholamines after cerebral infarction.
MedLine Citation:
PMID:  3282745     Owner:  NLM     Status:  MEDLINE    
Blood pressure, both venous and urinary catecholamines and plasma renin activity (PRA) were studied in 10 patients (6 men and 4 women, mean age 70 +/- 10 years) on the first three days after cerebral infarction. Blood pressure fell significantly (p less than 0.02) on the second and third day after stroke. There was a small but significant (p less than 0.01) decrease in plasma epinephrine concentration on the third day. The norepinephrine values remained constant on the three days. The PRA showed a significant (p less than 0.01) rise on the third day. No significant correlation was detected between the course of the blood pressure and the plasma catecholamines or PRA. When blood pressure was correlated with the urinary catecholamines, however, a significant correlation with epinephrine (r = 0.45; p less than 0.05) and with norepinephrine (r = 0.44; p less than 0.05) was found. We conclude that the changes in blood pressure after stroke are at least partly mediated by the changes in catecholamine production.
P A Jansen; T Thien; F W Gribnau; B P Schulte; J J Willemsen; K J Lamers; E F Poels
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  90     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  1988  
Date Detail:
Created Date:  1988-05-31     Completed Date:  1988-05-31     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  41-5     Citation Subset:  IM    
Department of Medicine, University of Nijmegen, the Netherlands.
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MeSH Terms
Aged, 80 and over
Blood Pressure*
Catecholamines / metabolism*
Cerebral Infarction / metabolism*,  physiopathology
Dopamine / metabolism
Epinephrine / metabolism
Middle Aged
Norepinephrine / metabolism
Renin / metabolism
Time Factors
Reg. No./Substance:
0/Catecholamines; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; EC

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