Document Detail

Blood pool contrast-enhanced MRA: improved arterial visualization in the steady state.
MedLine Citation:
PMID:  12846433     Owner:  NLM     Status:  MEDLINE    
Blood pool agents (BPAs) for contrast-enhanced magnetic resonance angiography (CE-MRA) allow prolonged imaging during the steady state when the agent is distributed through the complete vascular system. This increases both the spatial resolution and the contrast resolution. However, simultaneous venous and arterial enhancement hampers interpretation. For the pelvic region of the vasculature, it is shown that arterial visualization in this equilibrium phase can be improved if the central arterial axis (CAA) is known. However, manually obtaining this axis is not feasible in clinical practice. Therefore, a method is presented that utilizes images acquired during the first pass of the contrast agent to find the CAA in the steady-state data with minimum user initialization. The accuracy of the resulting CAA is compared with tracings of three observers in six patient datasets. It was found that the mean difference between the semiautomatic method and the manual delineation is 1.32 mm in the steady-state data, and that the resulting CAA was always within the arterial lumen, which is an important prerequisite for both improved visualization and segmentation.
Cornelis M van Bemmel; Onno Wink; Bert Verdonck; Max A Viergever; Wiro J Niessen
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Validation Studies    
Journal Detail:
Title:  IEEE transactions on medical imaging     Volume:  22     ISSN:  0278-0062     ISO Abbreviation:  IEEE Trans Med Imaging     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-07-08     Completed Date:  2003-10-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8310780     Medline TA:  IEEE Trans Med Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  645-52     Citation Subset:  IM    
Image Sciences Institute, University Medical Center, Room E.01.334, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
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MeSH Terms
Arteries / anatomy & histology*
Contrast Media
Image Enhancement / methods
Image Interpretation, Computer-Assisted / methods*
Imaging, Three-Dimensional / methods*
Magnetic Resonance Angiography / methods*
Pattern Recognition, Automated
Pelvis / anatomy & histology*,  blood supply*
Quality Control
Signal Processing, Computer-Assisted
Veins / anatomy & histology*
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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