Document Detail

Blood parameters in adults with intellectual disability at rest and after endurance exercise.
MedLine Citation:
PMID:  19089748     Owner:  NLM     Status:  MEDLINE    
Clinically, adult with intellectual disability (ID) appear less physically fit than people without ID, yet formal endurance evaluation has not been reported previously. We hypothesized that the immune system in adults people with ID can be influenced positively from 4 weeks of endurance training. Healthy subjects with ID ages from 43 to 55 years were included in the study. The subjects (n = 22) exercised on a treadmill for 30-40 min/d for 4 day/wk/4 wks. Blood samples were drawn at rest and immediately after the last exercise training. Plasma concentration of creatine kinase (CK), myoglobin (Mb), glutamine, and uric acid (UA) as biomarkers of muscle stress were measured. The results indicate that following the exercise program, the plasma glutamine and UA increased significantly (p < 0.05) from pre-to post-training levels, whereas CK isoenzyme and Mb levels showed no changes. In conclusion, 4 weeks of endurance training increased concentration of plasma glutamine and UA, which might be useful in the monitoring of training responses in adults with ID.
Eli Carmeli; Asad Bachar; Joav Merrick
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Research in sports medicine (Print)     Volume:  16     ISSN:  1543-8635     ISO Abbreviation:  Res Sports Med     Publication Date:  2008  
Date Detail:
Created Date:  2008-12-17     Completed Date:  2009-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167637     Medline TA:  Res Sports Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  272-80     Citation Subset:  IM    
Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.
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MeSH Terms
Body Mass Index
Creatine Kinase / blood
Exercise Therapy*
Exercise Tolerance / physiology*
Glutamine / blood
Mental Retardation / blood*,  physiopathology,  rehabilitation*
Middle Aged
Myoglobin / blood
Plasma Volume
Rest / physiology
Uric Acid / blood
Reg. No./Substance:
0/Myoglobin; 56-85-9/Glutamine; 69-93-2/Uric Acid; EC Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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