Document Detail

Blood-oxygen binding in healthy Standardbred horses.
MedLine Citation:
PMID:  15727917     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to determine the effect of regulating factors on the oxygen equilibrium curve (OEC) under standard conditions and then to calculate the oxygen extraction between arterial and jugular venous blood in healthy Standardbred horses. The results were compared to those previously obtained in humans and cattle, using the same experimental method. The partial oxygen pressure at 50% saturation of haemoglobin, measured under standard conditions (standard P50), was 24.8+/-2.0 (SD of mean) mmHg. This value was similar to the cattle standard P50 (25.0+/-1.4 mmHg, SD of mean) but lower than the human standard P50 (26.6+/-1.2 mmHg, SD of mean) previously reported using the same experimental method. The effects of regulating factors on the standard OEC were also determined, and a major effect of pH and temperature was noted. In contrast, partial carbon dioxide pressure played only a minor role in horses, compared to cattle and humans. No significant correlation was found between phosphate and chloride concentrations and standard P50.
C Cambier; N Di Passio; T Clerbaux; H Amory; V Marville; B Detry; A Frans; P Gustin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Veterinary journal (London, England : 1997)     Volume:  169     ISSN:  1090-0233     ISO Abbreviation:  Vet. J.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-02-24     Completed Date:  2005-04-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9706281     Medline TA:  Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  251-6     Citation Subset:  IM    
Department of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Veterinary Medicine, University of Liège, Liège B-4000, Belgium.
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MeSH Terms
Carbon Dioxide / blood
Hemoglobins / metabolism*
Horses / blood*
Hydrogen-Ion Concentration
Oxygen / blood*
Oxygen Consumption*
Reference Values
Reg. No./Substance:
0/Hemoglobins; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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