| Blood natural killer activity is reduced in men with occupational stress and job insecurity working in a university. | |
| | |
MedLine Citation:
|
PMID: 18941771 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To examine the immune response to job strain and insecurity of 88 men working in a university, divided according to age and type of employment. METHODS: Anxiety, job strain, job insecurity and subjective symptoms were measured by questionnaires. Blood NK cytotoxic activity was determined by an in vitro method and lymphocyte subpopulations by flow-cytometry analysis. RESULTS: Employees (over 40 years old) in a library showed higher values of job strain, anxiety and subjective symptoms and lower blood NK activity than the controls. The young employees with temporary employment showed high job insecurity and reduced blood NK activity, while the young sanitary staff with temporary position showed normal immune response. NK cytotoxic activity of the recruited men was negatively correlated with anxiety, work load and job insecurity. CONCLUSIONS: Not only anxiety and depression but also high levels of job strain and/or insecurity may affect the health status by reducing blood NK activity. |
| | |
Authors:
|
Paolo Boscolo; Angela Di Donato; Luca Di Giampaolo; Laura Forcella; Marcella Reale; Vincenzo Dadorante; Francesca Alparone; Stefano Pagliaro; Maria Kouri; Andrea Magrini; Emanuela Fattorini |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-10-22 |
Journal Detail:
|
Title: International archives of occupational and environmental health Volume: 82 ISSN: 1432-1246 ISO Abbreviation: Int Arch Occup Environ Health Publication Date: 2009 May |
Date Detail:
|
Created Date: 2009-05-04 Completed Date: 2009-07-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7512134 Medline TA: Int Arch Occup Environ Health Country: Germany |
Other Details:
|
Languages: eng Pagination: 787-94 Citation Subset: IM |
Affiliation:
|
Unit of Occupational Medicine, University G. D'Annunzio of Chieti-Pescara, Chieti, Italy. boscolo@unich.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anxiety / physiopathology, psychology* Humans Killer Cells, Natural / immunology* Male Middle Aged Occupational Exposure / adverse effects* Psychology, Industrial Stress, Psychological / etiology*, immunology Uncertainty Unemployment / psychology* Universities* Workload / psychology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Expression of nestin, desmin and vimentin in intact and regenerating muscle spindles of rat hind lim...
Next Document: Arsenic levels in ground water and cancer incidence in Idaho: an ecologic study.