Document Detail


Blood lipids, the risk factor of cerebral infarction.
MedLine Citation:
PMID:  8228699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A hospital-based case-control study was undertaken at Prasat Neurological Hospital and Institute, Bangkok, in 1990 to determine the association between blood lipid variables (i.e., total cholesterol and triglycerides) and cerebral infarction. To alleviate the unwanted effects of sample selection a number of inclusion and exclusion criteria were also made. A total of 193 newly diagnosed cerebral infarction patients together with an equal number of age-sex-matched controls, male and female 45 to 84 years of age, were studied. The association was assessed by logistic regression analysis. Other potential risk factors for cerebral infarction were entered in the logistic models as covariates to be adjusted. The results showed that, total cholesterol and triglycerides were statistically significant related to cerebral infarction (p < 0.0001) in univariated analysis. After adjusting for the covariates through multivariate logistic regression analyses, total cholesterol remained significantly related to cerebral infarction (p = 0.0430) but triglycerides was not significant (p = 0.3953). Other factors, namely, hypertension, cardiac impairment, diabetes mellitus and hemoglobin concentration were strongly related to cerebral infarction in both the univariate and multivariate analyses. The interaction between blood lipids variables and potential risk factors was also assessed. The finding showed significant multiplicative interaction between triglyceride levels and diabetes mellitus status (p = 0.0026). Other interaction terms did not approach statistical significance.
Authors:
A Vasuvat; S Towanabut
Related Documents :
22463919 - Prevalence of left and balanced coronary arterial dominance decreases with increasing a...
565019 - Broca aphasia: pathologic and clinical.
19199499 - Apolipoprotein e genotype and outcome after aneurysmal subarachnoid hemorrhage.
18035479 - Pediatric moyamoya disease presenting with intracerebral hemorrhage--report of three ca...
17320569 - Effect of prophylactically administered edaravone during antegrade cerebral perfusion i...
15210539 - Acute bilateral inferior cerebellar infarction in a patient with neurosyphilis.
7426159 - Variations in height of jugular "a" wave in relation to heart rate in normal subjects a...
2534279 - Thromboxane a2 in cardiovascular and renal disorders: is there a defined role for throm...
24463539 - Safety of combination therapy with milrinone and esmolol for heart protection during pe...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  76     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-12-17     Completed Date:  1993-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  109-16     Citation Subset:  IM    
Affiliation:
Prasat Neurological Hospital and Institute, Bangkok, Thailand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Case-Control Studies
Cerebral Infarction / blood*,  prevention & control
Cholesterol / blood
Developing Countries*
Female
Humans
Lipids / blood*
Male
Middle Aged
Risk Factors
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Lipids; 0/Triglycerides; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A prevalence survey of lipids abnormalities of rural area in Amphoe Phon, Khon Kaen.
Next Document:  Clinical comparison of patients with ankylosing spondylitis, Reiter's syndrome and psoriatic arthrit...