Document Detail

Blood lipids, the risk factor of cerebral infarction.
MedLine Citation:
PMID:  8228699     Owner:  NLM     Status:  MEDLINE    
A hospital-based case-control study was undertaken at Prasat Neurological Hospital and Institute, Bangkok, in 1990 to determine the association between blood lipid variables (i.e., total cholesterol and triglycerides) and cerebral infarction. To alleviate the unwanted effects of sample selection a number of inclusion and exclusion criteria were also made. A total of 193 newly diagnosed cerebral infarction patients together with an equal number of age-sex-matched controls, male and female 45 to 84 years of age, were studied. The association was assessed by logistic regression analysis. Other potential risk factors for cerebral infarction were entered in the logistic models as covariates to be adjusted. The results showed that, total cholesterol and triglycerides were statistically significant related to cerebral infarction (p < 0.0001) in univariated analysis. After adjusting for the covariates through multivariate logistic regression analyses, total cholesterol remained significantly related to cerebral infarction (p = 0.0430) but triglycerides was not significant (p = 0.3953). Other factors, namely, hypertension, cardiac impairment, diabetes mellitus and hemoglobin concentration were strongly related to cerebral infarction in both the univariate and multivariate analyses. The interaction between blood lipids variables and potential risk factors was also assessed. The finding showed significant multiplicative interaction between triglyceride levels and diabetes mellitus status (p = 0.0026). Other interaction terms did not approach statistical significance.
A Vasuvat; S Towanabut
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  76     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-12-17     Completed Date:  1993-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  109-16     Citation Subset:  IM    
Prasat Neurological Hospital and Institute, Bangkok, Thailand.
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MeSH Terms
Aged, 80 and over
Case-Control Studies
Cerebral Infarction / blood*,  prevention & control
Cholesterol / blood
Developing Countries*
Lipids / blood*
Middle Aged
Risk Factors
Triglycerides / blood
Reg. No./Substance:
0/Lipids; 0/Triglycerides; 57-88-5/Cholesterol

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