| Blood lactate concentrations during incremental exercise in subjects with sickle cell trait. | |
| | |
MedLine Citation:
|
PMID: 9588604 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of the present study was to assess blood lactate concentrations ([LA], mmol x L(-1)) and oxygen uptake (VO2, L x min(-1), mL x kg(-1) x min(-1)) during incremental exercise in subjects with sickle cell trait (SCT) only, i.e., sedentary subjects with SCT without anemia and/or associated alpha thalassemia. Anemia was ruled out using hemoglobin (Hb) level, and alphathalassemia was ruled out using hemoglobin S (HbS) percentage and concomitant Hb level and mean corpuscular volume (MCV). Comparison was made with control subjects with normal Hb, matched for physical fitness, anthropometric data, and hematological parameters. All subjects underwent an incremental exercise test (IET) using an electromagnetic cycle ergometer. Ventilatory data, i.e., minute ventilation (VE, L x min(-1)), oxygen uptake (VO2, mL x min(-1), mL x Kg(-1) x min(-1)) carbon dioxide production (VO2, mL x min(-1)), ventilatory equivalent for O2(VE x VO2(-1))and for CO2 (VE x VO2(-1)), and respiratory exchange ratio (RER, VO2 x VO2(-1)), were collected every minute during IET and the recovery period using a breath-by-breath automated system. Heart rate (HR, beats x min(-1)) was measured every minute using an EKG. Blood sampling was done every minute during IET and the first 5 min of the recovery period, and then every 5 min until the 20th minute of recovery. [LA] were determined by an enzymatic method with a spectrophotometer. Comparisons of all mean cardioventilatory variables showed no significant differences in subjects with SCT versus controls during IET and recovery. In contrast, analysis of variance revealed significantly lower time courses of [LA] during IET (P < 0.05) and recovery (P < 0.05), whereas time courses of VO2 were similar (P > 0.05). We conclude that the lower [LA] exhibited by subjects with SCT during incremental exercise and the subsequent recovery was not associated with concomitant oxygen uptake impairment. |
| | |
Authors:
|
A Bile; D Le Gallais; B Mercier; P Martinez; S Ahmaidi; C Prefaut; J Mercier |
Related Documents
:
|
8832544 - Cardiovascular and peak vo2 responses to supine exercise: effects of age and training s... 15556104 - Eat and run: prioritization of oxygen delivery during elevated metabolic states. 8531634 - Evaluation of the cosmed k2 telemetry system during exercise at moderate altitude. 16306254 - Cardiorespiratory responses to physical work during and following 17 days of bed rest a... 10362614 - Prior exercise increases net hepatic glucose uptake during a glucose load. 12648164 - Left ventricular volume changes during supine exercise in young endurance athletes. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Medicine and science in sports and exercise Volume: 30 ISSN: 0195-9131 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 1998 May |
Date Detail:
|
Created Date: 1998-07-07 Completed Date: 1998-07-07 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 649-54 Citation Subset: IM; S |
Affiliation:
|
Laboratoire de Physiologie des Interactions, Service d'E.F.R., Hôpital Arnaud de Villeneuve, Montpellier, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult African Continental Ancestry Group Exercise / physiology* Exercise Test Heart Rate Humans Lactic Acid / blood* Male Oxygen Consumption Physical Fitness / physiology* Sickle Cell Trait / physiopathology* |
| Chemical | |
Reg. No./Substance:
|
50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Delayed VO2 kinetics during ramp exercise: a criterion for cardiopulmonary exercise capacity in chro...
Next Document: Effects of a functional knee brace for ACL insufficiency during treadmill running.