Document Detail

Blood flow and muscle oxygen uptake at the onset and end of moderate and heavy dynamic forearm exercise.
MedLine Citation:
PMID:  11353679     Owner:  NLM     Status:  MEDLINE    
We hypothesized that forearm blood flow (FBF) during moderate intensity dynamic exercise would meet the demands of the exercise and that postexercise FBF would quickly recover. In contrast, during heavy exercise, FBF would be inadequate causing a marked postexercise hyperemia and sustained increase in muscle oxygen uptake (VO(2musc)). Six subjects did forearm exercise (1-s contraction/relaxation, 1-s pause) for 5 min at 25 and 75% of peak workload. FBF was determined by Doppler ultrasound, and O(2) extraction was estimated from venous blood samples. In moderate exercise, FBF and VO(2musc) increased within 2 min to steady state. Rapid recovery to baseline suggested adequate O(2) supply during moderate exercise. In contrast, FBF was not adequate during heavy dynamic exercise. Immediately postexercise, there was an approximately 50% increase in FBF. Furthermore, we observed for the first time in the recovery period an increase in VO(2musc) above end-exercise values. During moderate exercise, O(2) supply met requirements, but with heavy forearm exercise, inadequate O(2) supply during exercise caused accumulation of a large O(2) deficit that was repaid during recovery.
M C Van Beekvelt; J K Shoemaker; M E Tschakovsky; M T Hopman; R L Hughson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of physiology. Regulatory, integrative and comparative physiology     Volume:  280     ISSN:  0363-6119     ISO Abbreviation:  Am. J. Physiol. Regul. Integr. Comp. Physiol.     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-05-16     Completed Date:  2001-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100901230     Medline TA:  Am J Physiol Regul Integr Comp Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  R1741-7     Citation Subset:  IM    
Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
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MeSH Terms
Blood Pressure / physiology
Brachial Artery / physiology
Exercise / physiology*
Forearm / blood supply*,  physiology*
Lactic Acid / blood
Muscle, Skeletal / metabolism*
Osmolar Concentration
Oxygen / blood
Oxygen Consumption*
Reg. No./Substance:
50-21-5/Lactic Acid; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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