Document Detail


Blood flow in composite arterial grafts and effect of native coronary flow.
MedLine Citation:
PMID:  10585030     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Total arterial coronary revascularization can be achieved by joining arteries together as a composite graft with the proximal left internal mammary artery as the only source of blood inflow. Proof of the capacity of this composite conduit to provide adequate blood flow to the coronary circulation is required. METHODS: The radial artery was anastomosed to the left internal mammary artery as a Y graft in 17 patients and all coronary arteries grafted. Intraoperative blood flow through the composite grafts was evaluated by the transit-time Doppler technique. RESULTS: Against no resistance, blood flow in the left internal mammary artery alone was 99 +/- 9 mL/min and rose to 173 +/- 16 mL/min when the radial artery was anastomosed as a Y graft. Composite-graft flow following grafting was 88 +/- 9 mL/min, 49 +/- 6 mL/min when the aortic clamp was removed and native coronary flow restored and 82 +/- 13 mL/min following weaning from cardiopulmonary bypass. The maximal potential flow through the composite graft was 2.3-fold (95% CI 1.6 to 3.2) greater than that after cardiopulmonary bypass. CONCLUSIONS: Total arterial revascularization, using a composite graft, provided a 2.3-fold reserve of blood flow to the coronary vascular bed through the grafts.
Authors:
A G Royse; C F Royse; K L Groves; B Bus; G Yu
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  68     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1999 Nov 
Date Detail:
Created Date:  1999-12-14     Completed Date:  1999-12-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1619-22     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Parkville, Victoria, Australia. alistair.royse@nwhcn.org.au
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MeSH Terms
Descriptor/Qualifier:
Aged
Blood Flow Velocity / physiology
Coronary Angiography*
Coronary Artery Bypass / methods*
Coronary Circulation / physiology*
Coronary Disease / radiography,  surgery*
Female
Humans
Internal Mammary-Coronary Artery Anastomosis / methods*
Laser-Doppler Flowmetry
Male
Middle Aged
Postoperative Complications / radiography*
Radial Artery / transplantation*
Victoria
Comments/Corrections
Comment In:
Ann Thorac Surg. 2000 Jul;70(1):341-2   [PMID:  10921752 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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