Document Detail

Blood flow distributions by microsphere deposition methods.
MedLine Citation:
PMID:  10728307     Owner:  NLM     Status:  MEDLINE    
The art and science of the use of deposition markers for the estimation of blood flow distributions throughout the body and within organs is reviewed. Development of diffusible tracer techniques started 50 years ago. Twenty years later, radioactive 15 micron microspheres became the standard marker. Early studies on small animals, fetal sheep in 1967 and rats in 1976, provoked much of the technical development. Needs for avoiding the use of radioactivity, for having long lasting labels, and for providing higher spatial resolution, are driving the continuing exploration of newer techniques using colored and fluorescent microspheres and molecular deposition markers. Strengths and weaknesses of the various methods are compared.
F W Prinzen; J B Bassingthwaighte
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Publication Detail:
Type:  Comment; Journal Article; Review    
Journal Detail:
Title:  Cardiovascular research     Volume:  45     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-05-23     Completed Date:  2000-05-23     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  13-21     Citation Subset:  IM    
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MeSH Terms
Cardiac Output
Diagnostic Techniques, Cardiovascular
Regional Blood Flow*
Grant Support
P41 RR001243/RR/NCRR NIH HHS; P41 RR001243-210021/RR/NCRR NIH HHS
Comment On:
Cardiovasc Res. 2000 Jan 1;45(1):9-12   [PMID:  10728306 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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