Document Detail


Blood cell and iron status analytes of preterm and full-term infants from 20 weeks onwards during the first year of life.
MedLine Citation:
PMID:  20482297     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The goal of this study was to evaluate the dynamics of blood cell and iron status laboratory analytes in preterm and full-term infants during the first year of life.
METHODS: This was a prospective study of 100 preterm and 50 full-term infants. Preterm infants received iron supplementation beginning at 3 weeks of age. Laboratory tests were serially analyzed up to 12 months of corrected age.
RESULTS: Estimated means and the 95% reference intervals (RIs) from 20 weeks of age and onwards are presented separately for preterm and full-term infants. At the age of 20 weeks, mean hemoglobin (Hb) in preterm infants was lower than mean Hb in full-term infants, but this difference changed during follow-up. Ferritin concentrations were initially lower in preterm infants, but decreased to similar levels in both groups. Estimated mean values for transferrin receptor and reticulocyte Hb content were quite stable between the ages of 20 and 55 weeks in both groups.
CONCLUSIONS: Our study suggests that the same RIs for preterm and full-term infants can be used from the age of 20 or 30 weeks onwards, depending on the analyte. The RIs will help physicians detect iron deficiency or other problems of erythropoiesis in infants.
Authors:
Timo I Takala; Enni Mäkelä; Pauli Suominen; Jaakko Matomäki; Helena Lapinleimu; Liisa Lehtonen; Allan Rajamäki; Kerttu Irjala; Päivi M Lähteenmäki
Related Documents :
11389387 - Biomechanical factors influencing nuclear disruption of the intervertebral disc.
15666067 - Birth prematurity determines prolonged autonomic nervous system immaturity.
12598497 - Faecal elastase 1 levels in premature and full term infants.
16557867 - Immunoglobulins, secretory component, and transferrin in eye secretions of infants in r...
20456277 - Methaemoglobinaemia risk factors with inhaled nitric oxide therapy in newborn infants.
3801727 - Epidemiological study of congenital talipes calcaneovalgus.
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical chemistry and laboratory medicine : CCLM / FESCC     Volume:  48     ISSN:  1434-6621     ISO Abbreviation:  Clin. Chem. Lab. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-22     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9806306     Medline TA:  Clin Chem Lab Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1295-301     Citation Subset:  IM    
Affiliation:
Department of Clinical Chemistry, Turku University Hospital, Turku, Finland. timo.takala@tyks.fi
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Blood Cells / cytology*
Dietary Supplements
Female
Hematologic Tests / standards
Humans
Infant
Infant, Newborn
Iron / metabolism*
Male
Pregnancy
Premature Birth / blood*,  metabolism*
Reference Values
Term Birth / blood*,  metabolism*
Chemical
Reg. No./Substance:
7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Urine particle evaluation: a comparison between the UF-1000i and quantitative microscopy.
Next Document:  Non-invasive fetal RHD genotyping in the first trimester of pregnancy.