Document Detail

Blood cell and iron status analytes of preterm and full-term infants from 20 weeks onwards during the first year of life.
MedLine Citation:
PMID:  20482297     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The goal of this study was to evaluate the dynamics of blood cell and iron status laboratory analytes in preterm and full-term infants during the first year of life.
METHODS: This was a prospective study of 100 preterm and 50 full-term infants. Preterm infants received iron supplementation beginning at 3 weeks of age. Laboratory tests were serially analyzed up to 12 months of corrected age.
RESULTS: Estimated means and the 95% reference intervals (RIs) from 20 weeks of age and onwards are presented separately for preterm and full-term infants. At the age of 20 weeks, mean hemoglobin (Hb) in preterm infants was lower than mean Hb in full-term infants, but this difference changed during follow-up. Ferritin concentrations were initially lower in preterm infants, but decreased to similar levels in both groups. Estimated mean values for transferrin receptor and reticulocyte Hb content were quite stable between the ages of 20 and 55 weeks in both groups.
CONCLUSIONS: Our study suggests that the same RIs for preterm and full-term infants can be used from the age of 20 or 30 weeks onwards, depending on the analyte. The RIs will help physicians detect iron deficiency or other problems of erythropoiesis in infants.
Timo I Takala; Enni Mäkelä; Pauli Suominen; Jaakko Matomäki; Helena Lapinleimu; Liisa Lehtonen; Allan Rajamäki; Kerttu Irjala; Päivi M Lähteenmäki
Related Documents :
8557477 - Spontaneous and evoked otoacoustic emissions in pre-term and full-term neonates: is the...
20144647 - Long-term impact of neonatal injury in male and female rats: sex differences, mechanism...
805677 - Carbonic anhydrase isoenzymes in the erythrocytes of new-born premature and full-term i...
3978157 - Serum glutamic-oxaloacetic transaminase and glutamic-pyruvic transaminase activity in p...
11731657 - Neurobehavioral deficits in premature graduates of intensive care--potential medical an...
11849577 - Effect of general and epidural anaesthesia on thyroid hormones and immunity in neonates.
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical chemistry and laboratory medicine : CCLM / FESCC     Volume:  48     ISSN:  1434-6621     ISO Abbreviation:  Clin. Chem. Lab. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-22     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9806306     Medline TA:  Clin Chem Lab Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1295-301     Citation Subset:  IM    
Department of Clinical Chemistry, Turku University Hospital, Turku, Finland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Cells / cytology*
Dietary Supplements
Hematologic Tests / standards
Infant, Newborn
Iron / metabolism*
Premature Birth / blood*,  metabolism*
Reference Values
Term Birth / blood*,  metabolism*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Urine particle evaluation: a comparison between the UF-1000i and quantitative microscopy.
Next Document:  Non-invasive fetal RHD genotyping in the first trimester of pregnancy.