Document Detail


Blood cardioplegia does not increase haemolysis. A comparison between crystalloid and blood cardioplegia in coronary artery bypass grafting.
MedLine Citation:
PMID:  8857677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To study the effect of cardioprotection type on haemolysis, 100 patients scheduled for elective coronary artery bypass grafting were allocated to receive either blood cardioplegia (BCP) or crystalloid cardioplegia (CCP). Haemoglobin concentrations in plasma and urine were measured after induction of anaesthesia, 1 hour postoperatively and the next morning; blood acid-base status was determined at the end of cardiopulmonary perfusion; serum electrolytes and creatinine were measured before and 1 and 3 hours after the operation and serum creatinine also the next morning. Plasma haemoglobin values tended to be higher in the CCP than in the BCP group (47.6, 200.2 and 69.1 vs 31.5, 207.5 and 39.2 mg/l, p = 0.084). The urinary haemoglobin concentrations did not differ between the groups. The acid-base status showed greater buffer capacity with BCP technique. These results contradict association of blood cardioplegia technique with increased haemolysis during coronary artery bypass grafting.
Authors:
T T Rinne
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of thoracic and cardiovascular surgery     Volume:  30     ISSN:  0036-5580     ISO Abbreviation:  Scand J Thorac Cardiovasc Surg     Publication Date:  1996  
Date Detail:
Created Date:  1997-01-07     Completed Date:  1997-01-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0121343     Medline TA:  Scand J Thorac Cardiovasc Surg     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  IM    
Affiliation:
Department of Anesthesia and Intensive Care, Tampere University Hospital, Finland.
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MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium
Anesthesia, General
Blood*
Buffers
Cardioplegic Solutions / administration & dosage*
Cardiopulmonary Bypass
Coronary Artery Bypass*
Creatinine / blood
Heart Arrest, Induced*
Hemoglobins / analysis
Hemoglobinuria / urine
Hemolysis*
Humans
Isotonic Solutions
Plasma Substitutes / administration & dosage*
Potassium / blood
Sodium / blood
Surgical Procedures, Elective
Chemical
Reg. No./Substance:
0/Buffers; 0/Cardioplegic Solutions; 0/Hemoglobins; 0/Isotonic Solutions; 0/Plasma Substitutes; 0/crystalloid solutions; 60-27-5/Creatinine; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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