| Blood cadmium and moderate-to-severe glomerular dysfunction in Korean adults: analysis of KNHANES 2005-2008 data. | |
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MedLine Citation:
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PMID: 22252222 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: The objective of this study was to evaluate the association between blood cadmium (Cd) and moderate-to-severe glomerular dysfunction in a Korean population using a representative sample. METHODS: A cross-sectional study was used to evaluate the association between blood Cd and glomerular dysfunction. Based on the Korean National Health and Nutrition Examination Survey (2005-2008), individual blood Cd was measured in 2,992 adults, aged between 20 and 65. RESULTS: After adjusting for survey years, age, sociodemographic factors, and health behaviors, the odds ratio for moderate-to-severe glomerular dysfunction (<60 mL/min per 1.73 m(2)) was 1.97 (95% CI: 1.28-3.07) when comparing the highest with the lowest blood Cd quartile in Korean women. However, in Korean men, there was no association between blood Cd and moderate-to-severe glomerular dysfunction. CONCLUSIONS: These findings support the consideration of Cd as a risk factor for glomerular dysfunction in the female population. Furthermore, environmental heavy metal monitoring and an institutional strategy should be implemented to reduce Cd exposure in the general population. |
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Authors:
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Jun-Pyo Myong; Hyoung-Ryoul Kim; Dean Baker; Bongkyoo Choi |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-18 |
Journal Detail:
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Title: International archives of occupational and environmental health Volume: - ISSN: 1432-1246 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7512134 Medline TA: Int Arch Occup Environ Health Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Graduate School of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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