Document Detail

Blood-brain-barrier disruption in acute Wernicke encephalopathy: MR findings.
MedLine Citation:
PMID:  1939760     Owner:  NLM     Status:  MEDLINE    
The clinical and MR features of an alcoholic woman with Wernicke encephalopathy are reported. During the acute stage Gd-diethylenetriamine pentaacetic acid enhanced MR revealed damage of the blood-brain barrier bilaterally and symmetrically adjacent to the third ventricle, cerebral aqueduct, and fourth ventricle. The enhancement disappeared after successful thiamine therapy, as demonstrated in a repeat postcontrast MR 1 week later.
G Schroth; W Wichmann; A Valavanis
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  15     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    1991 Nov-Dec
Date Detail:
Created Date:  1991-12-04     Completed Date:  1991-12-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1059-61     Citation Subset:  IM    
Department of Neuroradiology, University Hospital, Zürich, Switzerland.
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MeSH Terms
Blood-Brain Barrier*
Brain Diseases, Metabolic / diagnosis,  drug therapy
Contrast Media
Follow-Up Studies
Gadolinium DTPA
Image Enhancement
Magnetic Resonance Imaging*
Organometallic Compounds / diagnostic use
Pentetic Acid / diagnostic use
Thiamine / therapeutic use
Wernicke Encephalopathy / diagnosis*
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 59-43-8/Thiamine; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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