Document Detail

Blood-aqueous barrier in newborn and young rabbits. An electron microscopic study.
MedLine Citation:
PMID:  946358     Owner:  NLM     Status:  MEDLINE    
Distribution of intravenously injected horseradish peroxidase (HRP) in the ciliary body of newborn and young (2 weeks old) rabbits was studied with the electron microscope. The reaction product was localized in all animals in the lumen of the blood vessels, in the perivascular area, in the surrounding connective tissue stroma and also in the epithelial cell layers. The peroxidase penetrated through the intercellular junctions of the pigmented cells to the intercellular space between the apical membranes of the two epithelial cell layers. In young rabbits peroxidase penetrated between the apical intercellular clefts of the non-pigmented cells in small quantities only, whereas in the newborn animals the clefts were filled with peroxidase. This reflects differences in the blood-aqueous barrier mechanism between the two studied groups and is evidently due to developmental stages of the eyes.
R Uusitalo; J Stjernschantz; A Palkama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  54     ISSN:  0001-639X     ISO Abbreviation:  Acta Ophthalmol (Copenh)     Publication Date:  1976 Feb 
Date Detail:
Created Date:  1976-04-15     Completed Date:  1976-04-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370347     Medline TA:  Acta Ophthalmol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  17-26     Citation Subset:  IM    
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MeSH Terms
Age Factors
Aqueous Humor
Ciliary Body / metabolism,  ultrastructure*
Epithelial Cells
Epithelium / ultrastructure
Eye / blood supply*
Horseradish Peroxidase / diagnostic use
Reg. No./Substance:
EC 1.11.1.-/Horseradish Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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