Document Detail


Blood ammonia--heart rate relationship during graded exercise is not influenced by glycogen depletion.
MedLine Citation:
PMID:  9506796     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The blood lactate (La) - heart rate (HR) relationship assessed during a graded maximal exercise test (GXT) is often used to provide training guidelines to athletes. Glycogen depletion is a condition that is known to influence the La response during a GXT and therefore can bias the interpretation of La curves. The purpose of our study was to determine an influence of glycogen depletion through long-term exercise (GDE) on blood La and ammonia (NH3) accumulation during a GXT. Eleven persons (5 males, 6 females; 26.3 +/- 4 yrs) performed a cycle ergometer GXT (3 min protocol) on two separate occasions with a 1-week interval. Using a randomized cross-over design, one of the two GXTs was preceded by a GDE. After GDE, blood NH3 increased more rapidly in the depleted versus control state whereas La increased less rapidly in the depleted state. The NH3 to HR relationship was not altered by glycogen depletion. We conclude, therefore, that determination of NH3 during a GXT may provide helpful additional information for training recommendations which is not available through La determination only.
Authors:
J Roeykens; L Magnus; R Rogers; R Meeusen; K De Meirleir
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  International journal of sports medicine     Volume:  19     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-04-08     Completed Date:  1998-04-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  26-31     Citation Subset:  IM; S    
Affiliation:
Vrije Universiteit Brussel, Dept. Human Physiology--Fac LK, Brussels, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Adult
Ammonia / blood*
Analysis of Variance
Cross-Over Studies
Exercise / physiology*
Exercise Test
Female
Glycogen / metabolism*
Heart Rate / physiology*
Humans
Lactic Acid / blood
Male
Muscles / metabolism*
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid; 7664-41-7/Ammonia; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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