Document Detail


Common factors regulating patterning of the nervous and vascular systems.
MedLine Citation:
PMID:  19575651     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The vascular and the nervous systems of vertebrates share many features with similar and often overlapping anatomy. The parallels between these two systems extend to the molecular level, where recent work has identified ever-increasing similarities between the molecular mechanisms employed in the specification, differentiation, and patterning of both systems. This review discusses some of the most recent literature on this subject, with particular emphasis on the roles that the Ephrin, Semaphorin, Netrin, and Slit signaling pathways play in vascular development.
Authors:
Mariana Melani; Brant M Weinstein
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural; Review    
Journal Detail:
Title:  Annual review of cell and developmental biology     Volume:  26     ISSN:  1530-8995     ISO Abbreviation:  Annu. Rev. Cell Dev. Biol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-08     Completed Date:  2010-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9600627     Medline TA:  Annu Rev Cell Dev Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  639-65     Citation Subset:  IM    
Affiliation:
Program in Genomics of Differentiation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Vessels / embryology*,  metabolism
Body Patterning
Cardiovascular System / embryology
Humans
Intercellular Signaling Peptides and Proteins / metabolism
Nervous System / embryology*,  metabolism
Vertebrates / embryology
Chemical
Reg. No./Substance:
0/Intercellular Signaling Peptides and Proteins

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