| Blood Transfusions in Radical Prostatectomy: A Contemporary Population-based Analysis. | |
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MedLine Citation:
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PMID: 22310749 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To examine the homologous blood transfusion (HBT), autologous blood transfusion (ABT) and intraoperative blood conservation technique (IOBCT) rates and trends at open (ORP) and minimally invasive radical prostatectomy (MIRP). METHODS: The Nationwide Inpatient Sample was queried. Multivariable logistic regression models focused on all three transfusion types. Covariables consisted of procedure specific annual hospital caseload (AHC), year of surgery, age, Charlson Comorbidity Index, and region. RESULTS: Overall, 119,966 patients underwent radical prostatectomy between 1998 and 2007. The HBT, ABT, and IOBCT rates were 6.2%, 6.0%, and 1.2%, respectively. HBT rates ranged from 5.1-5.1% between 1998 and 2007 (P = .49) vs 9.4-2.7% (P < .001) for ABT vs 1.9-0.9% (P = .003) for IOBCT in the same time period, respectively. In multivariable analyses, ORP patients treated at intermediate (odds ratio [OR] 1.48, P = .003) and low (OR 2.73, P < .001) AHC institutions were more likely to receive an HBT than ORP patients treated at high AHC institutions. Conversely, MIRP patients treated at high (OR 0.46, P = .040), intermediate (OR 0.27, P = .001), and low (OR 0.59, P = .015) AHC institutions were less likely to receive an HBT than ORP patients treated at high AHC institutions. CONCLUSION: Our results indicate that the overall transfusion rate at radical prostatectomy decreased within the last decade because of a substantial decline in ABT use. Moreover, MIRP protects from HBT, even when performed at low AHC Centers. |
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Authors:
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Jan Schmitges; Maxine Sun; Firas Abdollah; Quoc-Dien Trinh; Claudio Jeldres; Lars Budäus; Marco Bianchi; Jens Hansen; Thorsten Schlomm; Paul Perrotte; Markus Graefen; Pierre I Karakiewicz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Urology Volume: 79 ISSN: 1527-9995 ISO Abbreviation: Urology Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0366151 Medline TA: Urology Country: United States |
Other Details:
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Languages: eng Pagination: 332-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Martini-Clinic, Prostate Cancer Center Hamburg-Eppendorf, Hamburg, Germany; Cancer Prognostics and Health Outcomes Unit, University of Montréal Health Center, Montreal, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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