| Blood Transfusion Safety in Africa: A Literature Review of Infectious Disease and Organizational Challenges. | |
| | |
MedLine Citation:
|
PMID: 21872426 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Blood safety remains an important public health concern in Africa where lack of availability or provision of unsafe blood adversely impacts morbidity and mortality in the region. In recognition of this shortfall, the World Health Organization (WHO) established a goal of regional blood safety by 2012 through improved "organization and management, blood donor recruitment and collection, testing of donor blood as well as appropriate clinical use of blood" (Tagny et al: Transfusion. 2008;48:1256-1261; Tapko et al: Status of Blood Safety in the WHO African Region: Report of the 2006 Survey http://www.afro.who.int/en/divisions-a-programmes/dsd/health-technologies-a-laboratories.html. Brazzaville, Republic of Congo: WHO Regional Office for Africa; 2006). Although there has been substantial progress toward meeting these objectives, there are continued obstacles to both development and sustainability. In a setting where transfusion oversight is still being improved, transfusion-transmitted infections are of real concern. The high prevalence of some transfusion-transmissible agents such as hepatitis B virus and HIV in the general population means that some infected blood units escape detection by even well-performed laboratory testing, resulting in potential downstream transmission to patients. The spectrum of transfusion-transmitted infection include conventional as well as exotic pathogens, many of which are endemic to the region, thereby imparting ongoing challenges to recruitment and testing strategies. |
| | |
Authors:
|
Evan M Bloch; Marion Vermeulen; Edward Murphy |
Related Documents
:
|
776436 - External detection and visualization of myocardial ischemia with 11c-substrates in vitr... 8418276 - Validation of nitrogen-13-ammonia tracer kinetic model for quantification of myocardial... 6617706 - Effect of temperature on the arrested heart exposed to a 4-hour ischemia during blood p... 11919176 - Myocardial proteome analysis reveals reduced nos inhibition and enhanced glycolytic cap... 8633506 - Sequential evaluation of portal venous hemodynamics by doppler ultrasound in patients w... 12820076 - Effect of head elevation on cerebral blood flow velocity in post-cerebral operation pat... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-8-25 |
Journal Detail:
|
Title: Transfusion medicine reviews Volume: - ISSN: 1532-9496 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
|
Created Date: 2011-8-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8709027 Medline TA: Transfus Med Rev Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Inc. All rights reserved. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The PRISMA Symposium 2: Lessons from Beyond Europe. Reflections on the Evolution of Palliative Care ...
Next Document: Improving Safety for Young Blood Donors.