| Blood Fluidity Enhancement by Electrical Acupuncture Stimulation is Related to an Adrenergic Mechanism. | |
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MedLine Citation:
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PMID: 22309904 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We have reported that electrical acupuncture stimulation (ACU) increases blood fluidity by decreasing platelet aggregation. In this study, we investigated the mechanism causing the increase of blood fluidity. The effects of ACU on blood fluidity and platelet adhesion were examined using a Micro Channel Array Flow Analyzer (MC-FAN) and a laser scattering platelet aggregometer (PA-20). Male Wistar rats (7-8 weeks old) were used in the study. ACU (1 or 100Hz, 3-5V), which causes slight muscle twitching, was applied to the ZuSanli (ST-36) acupoint for 15 or 60 minutes once/day. Blood samples were collected from the inferior vena cava. ACU applied to ST-36 revealed significant increases in blood fluidity, while platelet adhesion activity decreased, regardless of the difference of stimulus time. The acupuncture had an immediate effect. Even if naloxone was administered during acupuncture stimulus, the blood flow time shortened in a similar way, as in the only acupuncture stimulus group. In addition, the effect of acupuncture on blood fluidity was inhibited by a β-antagonist. The results indicate that ACU affects blood fluidity depending on the acupoints, and that the effect of ACU might involve an endogenous adrenergic mechanism. |
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Authors:
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Shintaro Ishikawa; Hiroki Suga; Masaya Fukushima; Atsuhiro Yoshida; Yuri Yoshida; Masataka Sunagawa; Tadashi Hisamitsu |
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Publication Detail:
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Type: Journal Article Date: 2011-12-17 |
Journal Detail:
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Title: Journal of acupuncture and meridian studies Volume: 5 ISSN: 2005-2901 ISO Abbreviation: J Acupunct Meridian Stud Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101490763 Medline TA: J Acupunct Meridian Stud Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 21-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2012. Published by Elsevier B.V. |
Affiliation:
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Department of Physiology, School of Medicine, Showa University, Tokyo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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