| Blocking Effect on Adsorption-Controlled Electrochemiluminescence of CdSe Nanoparticles for Detection of the Neurotransmitter Serotonin. | |
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MedLine Citation:
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PMID: 21472993 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Herein, we have designed a special strategy for detection of the important neurotransmitter serotonin by coupling the electrodeposition of serotonin oxidative products with the adsorption-controlled anodic electrochemiluminescent dynamics of the CdSe-triethylamine system. The stable electrochemiluminescent emission is found to decline in the presence of serotonin. This uncommon inhibition is attributed to the gradual accumulation of the electropolymerized serotonin products, which decrease the adsorbance of CdSe nanoparticles on the glass carbon electrode, as demonstrated by the scanning electron microscopic images (SEM) and the stripping voltammetric identification. Based on the inhibition effect, a facile strategy has been developed to sensitively detect the serotonin ranging from 0.2-10 μM, with a detection limit of 0.1 μM. The interference from the common species including ascorbic acid and uric acid has been investigated. The recovery rates in the spiked serum samples range from 94-112 %, thereby implicating its potential applications in the complex bioassays. |
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Authors:
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Hui Jiang; Xuemei Wang |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-5 |
Journal Detail:
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Title: Chemistry, an Asian journal Volume: - ISSN: 1861-471X ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101294643 Medline TA: Chem Asian J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory), Southeast University, No.2 Sipailou, Nanjing, 210096 (People's Republic of China), Fax: (+86) 25-83792177. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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