Document Detail

Blink-startle reflex habituation in 30-34-week low-risk fetuses.
MedLine Citation:
PMID:  15841611     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate whether the blink-startle reflex (BSR) is a good marker of habituation to vibroacoustic stimulation in healthy preterm fetuses. MATERIALS AND METHODS: A total of 22 women with uncomplicated pregnancies at 30-34 weeks participated in the study. Vibroacoustic stimulus was repeatedly applied to the maternal abdomen above the fetal head for a period of 2 s every 10 s. Fetal eye tightening monitored by ultrasound within 2 s of the stimulus was considered a positive response. The habituation rate was defined as the number of stimuli applied before the fetus stopped responding to two consecutive stimuli. Results were compared using the Mann-Whitney U-test. RESULTS: All 22 fetuses showed habituation at a rate that varied from 1 to 9 (mean 4.2+/-1.8). CONCLUSION: BSR is a good marker of habituation in preterm fetuses. Further study is needed to ascertain whether abnormal BSR habituation could be a sign of fetal distress.
Carlo V Bellieni; Filiberto Severi; Catarina Bocchi; Ninetta Caparelli; Franco Bagnoli; Giuseppe Buonocore; Felice Petraglia
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  33     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2005  
Date Detail:
Created Date:  2005-04-21     Completed Date:  2005-05-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  33-7     Citation Subset:  IM    
Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy.
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MeSH Terms
Acoustic Stimulation
Blinking / physiology*
Fetus / physiology*
Gestational Age
Habituation, Psychophysiologic
Predictive Value of Tests
Pregnancy Trimester, Third
Reference Values
Startle Reaction / physiology*
Ultrasonography, Prenatal

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