Document Detail


Blink reflex in motor neuron disease.
MedLine Citation:
PMID:  16218200     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the study was to analyse the diagnostic value of blink reflex (BR) in motor neuron disease (MND). We studied 25 patients with MND including amyotrophic lateral sclerosis (ALS) in 18 patients, primary muscular atrophy (PMA) in 4 patients, and primary lateral sclerosis (PLS) in 3 patients and 12 healthy volunteers. The blink reflex was obtained in typical way. In ALS group, statistically significant increase in latency and decreased amplitude of R2 responses were found compared to the control group (p < 0.05), whereas BR in patients with PLS and PMA was within normal limits. The presence of low amplitude of R2 responses in patients with ALS may suggest loss of lower brainstem neurons connecting trigeminal and facial system, and probably also decreased facilitator effect of central nervous system on reticular formation in the brainstem.
Authors:
E Szmidt-Sałkowska; K Rowińska-Marcińska
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Electromyography and clinical neurophysiology     Volume:  45     ISSN:  0301-150X     ISO Abbreviation:  Electromyogr Clin Neurophysiol     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-10-12     Completed Date:  2005-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0327533     Medline TA:  Electromyogr Clin Neurophysiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  313-7     Citation Subset:  IM    
Affiliation:
Department of Neurology, Medical University of Warsaw, Poland. ela.szmidt@wp.pl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Amyotrophic Lateral Sclerosis / complications,  physiopathology*
Blinking / physiology*
Case-Control Studies
Electromyography
Humans
Middle Aged
Motor Neuron Disease / physiopathology*
Muscle, Skeletal / physiopathology
Muscular Atrophy / physiopathology*
Neural Conduction / physiology
Respiratory Insufficiency / etiology,  physiopathology
Tongue / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Differential diagnosis of intractable lateral knee pain with progressive symptoms: a case problem.
Next Document:  Pharmaceutical development of a parenteral lyophilised formulation of the investigational anticancer...