Document Detail


Bleomycin-induced pulmonary nodules: a variant of bleomycin pulmonary toxicity.
MedLine Citation:
PMID:  2445636     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bleomycin has been associated with pulmonary toxicity which is typically manifested as an interstitial pneumonitis resulting in fine, diffuse reticular or reticulomicronodular infiltrates. Attention is drawn to an additional radiologic appearance where discrete pulmonary nodules are seen and representative of bleomycin-induced change. The pitfalls of interpreting such changes as toxic effects versus metastatic disease and proposed mechanisms of bleomycin pulmonary toxicity are discussed.
Authors:
P K Zucker; N F Khouri; N B Rosenshein
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Gynecologic oncology     Volume:  28     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-01-19     Completed Date:  1988-01-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  284-91     Citation Subset:  IM    
Affiliation:
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Bleomycin / adverse effects*,  therapeutic use
Female
Humans
Lung / radiography
Lung Diseases / chemically induced*,  radiography
Neoplasms, Germ Cell and Embryonal / drug therapy
Ovarian Neoplasms / drug therapy
Chemical
Reg. No./Substance:
11056-06-7/Bleomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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