Document Detail


Bleeding manifestations of dengue haemorrhagic fever in Malaysia.
MedLine Citation:
PMID:  6111919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Analysis of the bleeding manifestations of 130 cases of dengue haemorrhagic fever admitted into the Children's ward of the General Hospital, Kuala Lumpur from May 1973 to September 1978 has been done. Petechial skin rash, epistaxis and gum bleeding were seen most commonly in mild and moderately severe cases. However, blood stained gastric aspirates, and severe haematemesis were seen in severe or very severe cases. Though with better vector control and preventive measures, a marked reduction in the incidence of the cases has been noted, severe cases were seen with symptoms of shock and gastrointestinal bleeding. These symptoms carried a bad prognosis. Among 15 children that died 10 had gastrointestinal bleeding and 2 had a disseminated intravascular coagulation defect. Lymphocytosis with atypical lymphocytes, low platelet count, low reticulocyte count and raised packed cell volume were the main haematological features seen in all these cases. All these features reverted to normal within a week. Mild evidence of disseminated intravascular coagulation was seen in a number of cases, but severe features were seen only in four. Two cases improved as a result of heparin therapy.
Authors:
R George; G Duraisamy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta tropica     Volume:  38     ISSN:  0001-706X     ISO Abbreviation:  Acta Trop.     Publication Date:  1981 Mar 
Date Detail:
Created Date:  1981-06-13     Completed Date:  1981-06-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370374     Medline TA:  Acta Trop     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  71-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Child
Child, Preschool
Continental Population Groups
Dengue / complications*,  epidemiology,  mortality
Female
Hemorrhage / etiology*
Humans
Infant
Malaysia
Male
Seasons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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