| Bleeding in acute promyelocytic leukemia (APL): fibrinolysis or defibrination? | |
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MedLine Citation:
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PMID: 1945823 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The coagulation abnormalities in 20 cases of acute promyelocytic leukemia (APL) treated at a single institution were reviewed. A remarkably uniform picture of defibrination and increased FDPs with well-preserved levels of other coagulation factors including AT-III was seen. Our data, together with those available in the literature, do not support DIC as the underlying mechanism of bleeding but seem rather to point to increased proteolysis as the cause. |
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Authors:
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I Krsnik; A Escribá; M López-Rubio; C Alarcón; E del Potro; J Díaz-Mediavilla |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nouvelle revue française d'hématologie Volume: 33 ISSN: - ISO Abbreviation: Nouv Rev Fr Hematol Publication Date: 1991 |
Date Detail:
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Created Date: 1991-12-06 Completed Date: 1991-12-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7909092 Medline TA: Nouv Rev Fr Hematol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 39-41 Citation Subset: IM |
Affiliation:
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Servicio de Hematología, Hospital Clínico de San Carlos, Madrid, Espagne. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Coagulation Disorders / etiology* Female Fibrin / metabolism* Fibrinolysis / physiology* Hemorrhage / etiology* Humans Leukemia, Promyelocytic, Acute / complications, physiopathology* Male Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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9001-31-4/Fibrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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