Document Detail

Blastomycosis of bones and joints.
MedLine Citation:
PMID:  17591310     Owner:  NLM     Status:  MEDLINE    
A retrospective study of 45 patients hospitalized with blastomycosis of bones or joints revealed 41 cases of osteomyelitis and 12 cases of septic arthritis. The majority were men (35 [78%] patients) and non-Aboriginal (32 [71%] patients). Median time from the onset of symptoms to hospitalization was shorter in women than men (male, 48 d; female, 14 d; P < 0.02), and shorter for Aboriginals than non-Aboriginals (non-Aboriginal, 50 d; Aboriginal, 19 d; P < 0.04). Cutaneous disease was present in 33 (73%) patients, and lung involvement was present in 29 (64%) patients. The most common osseous sites of involvement were the lower limb and axial skeleton. Common orthopaedic symptoms of bone lesions included bone pain in 42 (78%) patients, swelling in 32 (59%) patients, and soft tissue abscesses in 21 (39%) patients. Joint infection (12 patients) manifested as a monoarticular arthropathy presenting with effusion in 9 (75%) patients, pain in 8 (67%) patients, and decreased range of motion in 5 (42%) patients. Osseous blastomycosis can mimic bacterial infection and should be included in the differential diagnosis of bone and joint infection in patients who have visited or who live in geographic regions where B dermatitidis is endemic.
Mark Oppenheimer; John M Embil; Brian Black; Lyle Wiebe; Bill Limerick; Kerry MacDonald; Elly Trepman
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  100     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-26     Completed Date:  2007-07-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  570-8     Citation Subset:  AIM; IM    
Faculty of Medicine, Department of Medicine, Section of Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canad.
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MeSH Terms
American Native Continental Ancestry Group / statistics & numerical data
Arthritis, Infectious / diagnosis,  epidemiology,  microbiology*,  therapy
Blastomycosis* / diagnosis,  epidemiology,  therapy
Manitoba / epidemiology
Ontario / epidemiology
Osteomyelitis / diagnosis,  epidemiology,  microbiology*,  therapy
Retrospective Studies
Sex Distribution
Treatment Outcome

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