Document Detail


Blastocyst expansion score and trophectoderm morphology strongly predict successful clinical pregnancy and live birth following elective single embryo blastocyst transfer (eSET): a national study.
MedLine Citation:
PMID:  24114628     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To determine which characteristics of blastocyst embryo morphology may predict clinical pregnancy and live birth rates.
METHODS: A retrospective analysis of data from 3,151 cycles of fresh, non-donor eSET cycles from 2008 to 2009 was performed. Data were obtained from the Society for Assisted Reproductive Technologies (SART) underwent. All eSET were performed at the blastocyst stage. Main outcome measures were clinical pregnancy and live birth rates.
RESULTS: Trophectoderm morphology, embryo stage and patient age are highly significant independent predictors of both clinical pregnancy and live birth. Neither inner cell mass morphology nor embryo grade predicted clinical pregnancy or live birth.
CONCLUSIONS: Better trophectoderm morphology, younger patient age and further blastocyst progression all result in higher clinical pregnancy and live birth rates. Therefore, trophectoderm morphology and blastocyst stage should preferentially be used as the most important factors in choosing the best embryo for transfer.
Authors:
Stephanie Marshall Thompson; Ndidiamaka Onwubalili; Kelecia Brown; Sangita K Jindal; Peter G McGovern
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-10
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  -     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, 185 S. Orange Ave. E-506, Newark, NJ, 07103, USA, slmarshall4@gmail.com.
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