| Blackberry (Rubus spp.): a pH-dependent oral contrast medium for gastrointestinal tract images by magnetic resonance imaging. | |
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MedLine Citation:
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PMID: 16455409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study, seven fruits have been tested on their magnetic properties, paramagnetic metal content and contrast enhancement in magnetic resonance imaging (MRI) of phantom and in vivo. Magnetic susceptibility was determined for the fruit pulps, as well as the contents of paramagnetic metals; iron, manganese and copper. The total content of these metals was 4.3, 8.6, 11.1, 10.9, 12.3, 8.3 and 29.3 mg/kg of fruit for plum, blueberry, apple (red), pineapple, beet, grape, blackberry, respectively, and with magnetic susceptibility of -2.29+/-0.07, -2.43+/-0.07, -2.13+/-0.07, -1.84+/-0.02, -1.75+/-0.01, -1.78+/-0.06, -2.18+/-0.07 SI, respectively. T(1)- and T(2)-weighted MR images were performed for the seven fruits and water (chi= -9.98 x 10(-3) SI) and in one subject. While there was no correlation between the magnetic susceptibility and contrast enhancement, there is a correlation with the total paramagnetic metal content determined with contrast enhancement in MRI. Thus, blackberry (Rubus spp.) contrast enhancement was the highest among the fruits in T(1)-weighted images. Furthermore, this fruit's contrast enhancement shows to be pH-dependent. These characteristics and the wide availability of the Rubus spp. suggest that it should be implemented as an oral contrast agent in images by MR to assess the function of the gastric section of the GI tract. Furthermore, it has the advantage of being a natural meal, so that it can be well tolerated by the patients and use as much as it is needed without side effects. |
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Authors:
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María G Espinosa; Modesto Sosa; Luis M De León-Rodríguez; Teodoro Córdova; Jesus Bernal-Alvarado; Mario Avila-Rodríguez; Jose A Reyes-Aguilera; Juan J Ortíz; Fernando A Barrios |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2005-12-27 |
Journal Detail:
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Title: Magnetic resonance imaging Volume: 24 ISSN: 0730-725X ISO Abbreviation: Magn Reson Imaging Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-02-03 Completed Date: 2006-08-31 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8214883 Medline TA: Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 195-200 Citation Subset: IM |
Affiliation:
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Facultad de Física e Inteligencia Artificial, Universidad Veracruzana, 91090 Xalapa, Ver., México. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Contrast Media / administration & dosage* Fruit* Gastrointestinal Diseases / diagnosis* Humans Hydrogen-Ion Concentration Magnetic Resonance Imaging / methods* Phantoms, Imaging |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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