| Bisphosphonates: bone, muscle and joint pain. | |
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MedLine Citation:
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PMID: 19391290 Owner: HSR Status: MEDLINE |
Abstract/OtherAbstract:
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1) Comparative trials and reports by healthcare professionals show that severe and sometimes incapacitating muscle, joint and bone pain can occur days, months or years after beginning long-term oral bisphosphonate therapy. Patients treated for osteoporosis are particularly at risk; 2) This type of pain affects between 2% and 5% of patients, especially those taking an oral bisphosphonate once a week; 3) The role of a bisphosphonate should be considered when a patient presents with musculoskeletal pain. Discontinuation of bisphosphonate therapy can be tried and may represent a better option than escalation of analgesic therapy. |
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Authors:
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- |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Prescrire international Volume: 18 ISSN: 1167-7422 ISO Abbreviation: Prescrire Int Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-04-24 Completed Date: 2009-04-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9439295 Medline TA: Prescrire Int Country: France |
Other Details:
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Languages: eng Pagination: 23 Citation Subset: T |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arthralgia
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chemically induced* Diphosphonates / adverse effects* Humans Musculoskeletal Diseases / chemically induced* Osteoporosis / drug therapy Pain / chemically induced* |
| Chemical | |
Reg. No./Substance:
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0/Diphosphonates |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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