Document Detail


Bisphosphonate-related osteonecrosis of the jaw presenting as a cutaneous dental sinus tract: a case report and review of the literature.
MedLine Citation:
PMID:  20153079     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bisphosphonates are endogenous pyrophosphate analogs that work to inhibit osteoclast activity. They are commonly used in the treatment of patients with bone related diseases, such as solid tumor metastasis and osteoporosis. One of the infrequent but not rare side effects, especially with high doses of bisphosphonates, is osteonecrosis of the jaw. Although predominantly recognized by dentists because of the bony and intraoral manifestations of the disease, it may also present on the skin. We present a case of osteonecrosis of the jaw resembling two flesh-colored papules associated with dental sinus tracts to highlight the clinical manifestations that dermatologists may encounter, and review the literature on this rare but morbid condition.
Authors:
Sam V Truong; Linda C Chang; Timothy G Berger
Related Documents :
20670089 - Recovery of orbital fat pad prolapsus and deepening of the lid sulcus from topical bima...
17183839 - Sinus histiocytosis with massive lymphadenopathy--a review of seven cases.
11052249 - Choanal polyp of sphenoidal origin.
10750739 - A case report of sinonasal teratocarcinosarcoma.
2280159 - Septic shock and death due to occult sinusitis.
17403889 - Pneumosinus dilatans of the ethmoid sinus presenting with exophthalmus: a case report a...
24379599 - Meta-analysis of barrett's esophagus in china.
6568919 - Hemimasticatory and hemifacial spasm: a common pathophysiology?
19460649 - Camelid cardiology.
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-02-11
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  62     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-6     Citation Subset:  IM    
Copyright Information:
Copyright 2008 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
Affiliation:
Department of Dermatology, University of California-San Francisco, San Francisco, California, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged, 80 and over
Cutaneous Fistula / etiology*
Diphosphonates / adverse effects*
Female
Fistula / etiology*
Humans
Jaw Diseases / chemically induced*,  complications*,  pathology
Osteonecrosis / chemically induced*,  complications*
Periapical Diseases / etiology*
Chemical
Reg. No./Substance:
0/Diphosphonates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Periorbital mucinosis: A variant of cutaneous lupus erythematosus?
Next Document:  Redox agents modulate neuronal activity and reproduce physiological aspects of neuronal aging.