| Bisphenol-A: a new diabetogenic factor? | |
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MedLine Citation:
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PMID: 20687395 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this review was to analyze the potential effects of environmental chemicals on homeostatic control related to glycemia and energy balance. Many of the environmental chemicals can mimic or interfere with the action of hormones and are generally referred to as "endocrine disruptors". Among these compounds, polychlorinated biphenyls, dioxins, phthalates and bisphenol-A have been correlated with alterations in blood glucose homeostasis in humans. In rodents it has been demonstrated that small doses of bisphenol-A have profound effects on glucose metabolism. Therefore, this altered blood glucose homeostasis may enhance the development of type 2 diabetes. |
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Authors:
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Paloma Alonso-Magdalena; Ana Belin Ropero; Sergi Soriano; Ivan Quesada; Angel Nadal |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Hormones (Athens, Greece) Volume: 9 ISSN: 1109-3099 ISO Abbreviation: Hormones (Athens) Publication Date: 2010 Apr-Jun |
Date Detail:
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Created Date: 2010-08-06 Completed Date: 2010-08-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101142469 Medline TA: Hormones (Athens) Country: Greece |
Other Details:
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Languages: eng Pagination: 118-26 Citation Subset: IM |
Affiliation:
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CIBER of Diabetes and Associated Metabolic Diseases, CIBERDEM, lnstitute of Bioengineering, University Miguel Hernandez of Elche, Elche, Spain. palonso@umh.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Glucose / drug effects Diabetes Mellitus, Type 2 / blood, chemically induced* Endocrine Disruptors / adverse effects* Energy Metabolism / drug effects Environmental Pollutants / adverse effects* Estradiol / metabolism Estrogens, Non-Steroidal / adverse effects* Evidence-Based Medicine Homeostasis Humans Phenols / adverse effects* Risk Assessment Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Endocrine Disruptors; 0/Environmental Pollutants; 0/Estrogens, Non-Steroidal; 0/Phenols; 50-28-2/Estradiol; 80-05-7/bisphenol A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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