| Birthweight discordance, risk factors and its impact on perinatal mortality among Japanese twins: data from a national project during 2001-2005. | |
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MedLine Citation:
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PMID: 20874472 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Our aims were to assess the incidence of birthweight discordance of twins, to explore risk factors and its impact on perinatal mortality, and to quantify the risks at different severity of birthweight discordance in Japan, by using a nationwide obstetric database. There were 10,828 pairs of twins, born from 2001 to 2005 recorded in the database of the national Perinatal Health Care Project, fully enrolled. The overall incidence of birthweight discordance was 47.34%. The incidence of mild, severe and extremely severe discordance was 19.26%, 10.21% and 17.87%, respectively. The incidence of birthweight discordance in Japan is much higher than that in other countries, particularly at higher severity level. By linear regression model, our study added independent factors of primiparity (p < .001), sex composition (p < .001), chorionicity (p < .001), gestational age (p < .001), and delivery mode (p < .001) in determining birthweight discordance percentage. Maternal age and application of assisted reproduction technologies (ART) didn't significantly influence the birthweight discordance. The birthweight discordance is closely associated with gestational age and affected discharge mortality. From 25% of birthweight discordance, risk to discharge mortality tended to significantly increase, suggesting it should be added as a reference for clinical practices. |
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Authors:
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Ruoyan Gai Tobe; Rintaro Mori; Norio Shinozuka; Takahiko Kubo; Kazuo Itabashi |
Publication Detail:
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Type: Journal Article; Twin Study |
Journal Detail:
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Title: Twin research and human genetics : the official journal of the International Society for Twin Studies Volume: 13 ISSN: 1832-4274 ISO Abbreviation: Twin Res Hum Genet Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-29 Completed Date: 2010-12-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101244624 Medline TA: Twin Res Hum Genet Country: Australia |
Other Details:
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Languages: eng Pagination: 490-4 Citation Subset: IM |
Affiliation:
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Department of Global Health Policy, the University of Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asian Continental Ancestry Group / genetics* Birth Weight / genetics* Databases, Factual Female Gestational Age Humans Infant, Newborn Japan / epidemiology Linear Models Male Maternal Age Perinatal Mortality* Pregnancy Risk Factors Twins / genetics* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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