Document Detail

Birth weight and subsequent blood pressure: A meta-analysis.
MedLine Citation:
PMID:  22424328     Owner:  NLM     Status:  In-Data-Review    
Hypertension is becoming an important health problem in many countries. The 'small baby syndrome hypothesis' suggests that an inverse linear relationship exists between birth weight and later risk of hypertension; however, this relationship is under debate. We conducted a meta-analysis to examine the association between birth weight and subsequent blood pressure. Among 78 studies reporting on the association between birth weight and subsequent blood pressure, 20 articles (reporting 27 original studies) were eligible for inclusion. Low birth weight (<2500g) compared with birth weight greater than 2500g was associated with an increased risk of hypertension (odds ratio [OR] 1.21; 95% confidence interval [CI] 1.13, 1.30); high birth weight (>4000g) compared with birth weight less than 4000g was associated with a decreased risk of hypertension (OR 0.78; 95% CI 0.71, 0.86). When low birth weight (<2500g) was compared with birth weight greater than 2500g, mean systolic blood pressure (SBP) increased by 2.28mmHg (95% CI 1.24, 3.33); when high birth weight (>4000g) was compared with birth weight less than 4000g, mean SBP decreased by 2.08mmHg (95% CI -2.98, -1.17). These findings indicate that there is an inverse linear association between birth weight and later risk of hypertension, and that this association primarily exists between birth weight and SBP.
Min Mu; Su-Fang Wang; Jie Sheng; Yan Zhao; Hu-Zhong Li; Chuan-Lai Hu; Fang-Biao Tao
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Publication Detail:
Type:  Journal Article     Date:  2012-02-14
Journal Detail:
Title:  Archives of cardiovascular diseases     Volume:  105     ISSN:  1875-2128     ISO Abbreviation:  Arch Cardiovasc Dis     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-03-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101465655     Medline TA:  Arch Cardiovasc Dis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  99-113     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Masson SAS. All rights reserved.
School of Public Health, Anhui Medical University, Meishan road 69, Hefei 230032, Anhui, China.
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