Document Detail

Birth weight is lower for survivors of the vanishing twin syndrome: a case-control study.
MedLine Citation:
PMID:  17931633     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the outcome of singleton pregnancies originating from a twin gestation with singleton pregnancies originating from a single gestation. DESIGN: Case-control study. SETTING: Women's general hospital in Austria. PATIENT(S): A total of 794 singleton deliveries after IVF/intracytoplasmic sperm injection, including 46 survivors of vanishing twin syndrome (study group) and 92 matched singletons (control group). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Data concerning duration of gestation, mode of delivery, birth weight, neonatal intensive care unit admission, duration of hospitalization, perinatal mortality. RESULT(S): Of all singletons born, 5.8% originated from a twin gestation. Mean (+/- SD) birth weight was significantly higher in the control group (2876.3 +/- 600.5 g vs. 3249.6 +/- 624.5 g). The frequency of low birth weight (26.1% vs. 12.0%) and being small for gestational age (32.6% vs. 16.3%) was significantly lower in the control group. No differences were observed in terms of duration of gestation. CONCLUSION(S): A higher risk for lower birth weight and being small for gestational age for survivors of the vanishing twin syndrome was found. Such pregnancies need to be carefully monitored, and parents must be informed about the associated risks when transferring more than one embryo.
Omar Shebl; Thomas Ebner; Michael Sommergruber; Andreas Sir; Gernot Tews
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Publication Detail:
Type:  Journal Article     Date:  2007-10-10
Journal Detail:
Title:  Fertility and sterility     Volume:  90     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-01     Completed Date:  2008-08-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  310-4     Citation Subset:  IM    
IVF Unit, Landesfrauen- und Kinderklinik, and Department of Gynecology, Allgemeines Krankenhaus, Linz, Austria.
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MeSH Terms
Abortion, Missed
Birth Weight*
Case-Control Studies
Diseases in Twins
Fertilization in Vitro / adverse effects
Fetal Resorption
Infant, Low Birth Weight
Infant, Newborn
Infant, Small for Gestational Age
Pregnancy Outcome*
Pregnancy, Multiple*
Sperm Injections, Intracytoplasmic / adverse effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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