Document Detail

Birth weight and duration of breast-feeding: are the beneficial effects of human milk being overestimated?
MedLine Citation:
PMID:  3763277     Owner:  NLM     Status:  MEDLINE    
The beneficial effects of breast-feeding on infant mortality and morbidity have been demonstrated in many studies. Few of these, however, have taken into account the possible confounding effect of birth weight. Several studies have shown that babies of low birth weight are less likely to be breast-fed. In some circumstances, this alone may account for a more than twofold excess in postperinatal infant mortality rates among non-breast-fed babies, even in the absence of any beneficial effect of breast-feeding. The association between birth weight and breast-feeding and the magnitude of the confounding effect is illustrated using data from a longitudinal study of infant mortality in Pelotas, Southern Brazil, and also using published results from other studies. It is concluded that studies designed or analyzed to relate breast-feeding to infant mortality should take the confounding effect of birth weight into account to avoid overestimating the beneficial effects of human milk.
F C Barros; C G Victora; J P Vaughan; P G Smith
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatrics     Volume:  78     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-11-10     Completed Date:  1986-11-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  656-61     Citation Subset:  AIM; IM    
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MeSH Terms
Birth Weight*
Breast Feeding*
Evaluation Studies as Topic
Infant Mortality
Infant, Low Birth Weight
Infant, Newborn
Milk, Human / physiology
Socioeconomic Factors
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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