| Birth of a healthy boy after fertilization of cryopreserved oocytes with cryopreserved testicular spermatozoa from a man with nonmosaic Klinefelter syndrome. | |
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MedLine Citation:
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PMID: 17980871 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To report the first birth with frozen spermatozoa and frozen oocytes in a case of nonmosaic Klinefelter syndrome. DESIGN: Case report. SETTING: Private IVF clinics and a university hospital. PATIENT(S): A 32-year-old woman and a 33-year-old man. INTERVENTION(S): Testicular sperm extraction and cryopreservation, oocyte recovery and cryopreservation, intracytoplasmic sperm injection. MAIN OUTCOME MEASURE(S): Assessment of fertilization and chromosomal analysis of newborn child. RESULT(S): Three oocytes were injected and one embryo was obtained, resulting in the birth of a normal (46,XY) boy. CONCLUSION(S): Cryopreserved spermatozoa from a patient with nonmosaic Klinefelter syndrome can form normal embryos even with cryopreserved oocytes. |
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Authors:
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Ermanno Greco; Marcello Iacobelli; Laura Rienzi; Giuseppe F Menchini Fabris; Nicola Tesorio; Jan Tesarik |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-11-05 |
Journal Detail:
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Title: Fertility and sterility Volume: 89 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-04-14 Completed Date: 2008-04-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 991.e5-7 Citation Subset: IM |
Affiliation:
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Center for Reproductive Medicine, European Hospital, Rome, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Azoospermia / etiology, pathology, therapy* Cryopreservation* Embryo Transfer Female Humans Infant, Newborn Klinefelter Syndrome / complications*, pathology Live Birth Male Oocyte Retrieval Oocytes* Ovulation Induction Pregnancy Semen Preservation* Sperm Injections, Intracytoplasmic* Spermatozoa* Testis / pathology* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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