Document Detail


Birth defects among children born to a population occupationally exposed to pesticides in Colombia.
MedLine Citation:
PMID:  2389130     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case-referent study of birth defects was nested in a prevalence survey of adverse reproductive outcomes carried out among 8867 floriculture workers in Bogotá, Colombia. A total of 535 children born to these workers and reported by their parents as malformed and 1070 children selected at random as referents were invited to a medical examination including consultation with a geneticist and a clinical teratologist and a review of the medical records. Seventy-six percent of both groups attended the examination. Of 403 children reported as malformed, a birth defect was confirmed for only 154 (38%). On the other hand, of the 817 children reported as normal, 735 (90%) were normal, but 68 had a birth defect and 14 had other conditions. A case-referent analysis was then carried out including 222 children with birth defects and 443 referents. An increased risk was found only for birthmarks, and specifically for hemangiomas, for children with parents exposed to pesticides in the floriculture industry.
Authors:
M Restrepo; N Muñoz; N Day; J E Parra; C Hernandez; M Blettner; A Giraldo
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Scandinavian journal of work, environment & health     Volume:  16     ISSN:  0355-3140     ISO Abbreviation:  Scand J Work Environ Health     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-09-26     Completed Date:  1990-09-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7511540     Medline TA:  Scand J Work Environ Health     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  239-46     Citation Subset:  IM    
Affiliation:
Instituto Nacional de Salud, Sanidad del Ambiente, Bogotá, Colombia.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced / epidemiology*,  etiology
Adult
Agriculture*
Case-Control Studies
Child
Colombia
Environmental Exposure
Female
Hemangioma, Cavernous / chemically induced,  epidemiology
Humans
Male
Multivariate Analysis
Pesticides / adverse effects*
Pregnancy
Pregnancy Outcome / epidemiology*
Prevalence
Retrospective Studies
Risk Factors
Chemical
Reg. No./Substance:
0/Pesticides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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