| Birth cohort effects on incidence of lung cancers: a population-based study in Nagasaki, Japan. | |
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MedLine Citation:
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PMID: 11050464 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Smoking prevalence remains high (around 60%) among Japanese males, but smoking initiation among males born in the 1930s decreased by approximately 10% due to economic difficulties following World War II. The present study was designed to examine whether this temporary decline in smoking initiation influenced the subsequent incidence of lung cancers, especially adenocarcinoma. Trends of lung cancer incidence by histological type in both sexes were investigated using data from the population-based cancer registry in Nagasaki, Japan, from 1986 through 1995. During this period, 5668 males and 2309 females were diagnosed as having lung cancer, and the overall incidence of lung cancers among both sexes remained stable. However, males aged 55 - 59 years showed a decrease in the age-specific incidence of adenocarcinoma and squamous-cell carcinoma (P < 0.05 and P < 0.01, respectively). In birth cohort analyses, the incidence of adenocarcinoma and squamous-cell carcinoma was lower in the 1935 - 1939 birth male cohort than in the successive cohorts. The incidence of lung cancers among females with low smoking prevalence did not change with birth cohort. The low smoking initiation among the 1935 - 1939 birth male cohort appeared to have resulted in a decreased incidence of adenocarcinoma and squamous cell carcinoma among middle-aged Japanese males. The present study suggests that smoking prevention has an effect in reducing the incidence of lung adenocarcinoma, as well as squamous-cell carcinoma, among smokers. |
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Authors:
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H Soda; M Oka; M Soda; K Nakatomi; S Kawabata; M Suenaga; T Kasai; Y Yamada; S Kamihira; S Kohno |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese journal of cancer research : Gann Volume: 91 ISSN: 0910-5050 ISO Abbreviation: Jpn. J. Cancer Res. Publication Date: 2000 Oct |
Date Detail:
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Created Date: 2000-12-22 Completed Date: 2001-01-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8509412 Medline TA: Jpn J Cancer Res Country: JAPAN |
Other Details:
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Languages: eng Pagination: 960-5 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501, Japan. soda@net.nagasaki-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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epidemiology*,
etiology Adult Aged Cohort Studies Data Interpretation, Statistical Female Humans Incidence Japan / epidemiology Lung Neoplasms / epidemiology*, etiology Male Middle Aged Risk Factors Smoking / adverse effects* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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